A team
under the direction of Stanford cell physiologist and neuroscientist Tom
Sudhof, PhD, has shown that in human ESCs or iPSCs, just boosting the level of
a single transcription factor results in an abundant and quite pure population
of nerve cells within as little as two weeks.
And unlike
previous methods, this one seems to generate nerve cells of equally high
functional quality regardless of which “starter” cell line was used to get the
process underway.
Clearly, if
you’re doing regenerative medicine for a stroke or brain-trauma victim etc.,
you’re going to need a lot of nerve cells, and time is of the essence. So the
new method represents a major forward step toward the realization of the dream
of personalized regenerative medicine.
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